This project’s end deliverable is a computerized Clinical Decision Support tool for Lynch Syndrome screening that would tackle a health-care system-wide issue of tailoring routine clinical care to accommodate local needs, reflect a nationally developing standard of practice for universal colorectal cancer tumor testing for Lynch Syndrome, and address bioethical issues of informed consent and returning findings to patients and their families concerning heritable colorectal cancer. The aims are: 1. Identify through interviews with key content experts and decision-makers the critical health system elements and decision points for adaptation of colorectal tumor testing in two patient care settings; 2. Identify through interviews and targeted surveys of geneticists and non-geneticists the barriers, facilitators, and priorities for successfully deploying a local clinical decision support tool for diagnostic genetic tests that leverages the Electronic Medical Record; and 3. Test the decision support tool to evaluate clinical utility and appropriateness through evidence-based usability methods The improvement in care and information conveyance could, ultimately, save lives and deliver on the promise of personalized genomic medicine.
There are potential opportunities for students to assist in creating and testing a decision support prototype with partner clinics.
Project Keywords: Decision Support, Genomic Medicine, Implementation Science