Chair’s Message

We are moving toward our vision with a number of activities across our various programs. We have updated our strategic plan in response to the 10-year academic program review that we recently completed. For our research-oriented MS and PhD programs, we have recently added a specialization in Data Science. We are completing a curriculum revision for our on line applied clinical informatics MS which will be effective Fall 2020. The work of our fellows in the clinical informatics fellowship program has received plaudits from clinical administrators and faculty, and we are currently recruiting a new faculty member in our department to assist with this program (view position description).  We are also recruiting a faculty member in medical education to start Summer 2020 (view position description). This is the beginning of a new cycle of admissions to our graduate programs, and we look forward to another productive year, and new growth in our department.

Cordially,

Peter Tarczy-Hornoch, MD
Chair and Professor, Department of Biomedical Informatics and Medical Education

Biomedical Informatics and Medical Education Newsletter

March 20 – March 24, 2023

UPCOMING LECTURES AND SEMINARS

BIME 590
Title: Has My Post-Transplant Journey been Normal? Designing a novel benchmarking tool to support pediatric kidney transplant recipients and their families
Presenter: Ari Pollack, MD
Thursday, March 30^th – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]

Abstract: Many families impacted by kidney disease often don’t know other families also impacted by kidney disease. This leaves people wondering if their own journeys and experiences after transplant are typical or normal. Without this understanding, individuals may not know when to ask for help when things aren’t going well. We set out to understand how we could design a new tool that will help people compare their experiences after transplant. In this session, we will share our work from two different studies exploring first how to capture and structure the journeys families take after transplant, and secondly our work engaging stakeholders in a user centered design process to help design a new benchmarking tool. Finally, we will discuss future plans to conduct a technology probe to get feedback on this new comparison tool with patients, caregivers, and clinicians.

Presenter Bio: Dr. Ari Pollack is an Associate Professor of Pediatrics, within the division of Nephrology at Seattle Children’s Hospital, and the University of Washington, School of Medicine. In addition, he also is an Adjunct Associate Professor of Biomedical Informatics and Medical Education, as well as an Adjunct Associate Professor at the UW Information School. His research explores how the design of healthcare technology can improve clinical decision making for patients, families, and clinicians. Dr. Pollack combines his experiences and background in information science, clinical informatics, and clinical practice to improve outcomes for children living with chronic kidney disease. His current NIH funded work explores how information technology can help patients & families compare and contextualize their own experiences to that of others with similar conditions. In addition, driven by his own frustrations with current electronic health records, he has pursued and received funding to develop new clinician focused tools that reduce the cognitive burden associated with information retrieval and clinical decision making.

PUBLICATIONS & PRESENTATIONS
A panel with George Demiris, Anne Moen and Anne Turner has been accepted for the Medical Informatics Europe (MIE  2023) conference held in Gothenburg, Sweden May 22-25.  The panel is titled “Informatics Tools and Strategies to Promote Inclusive Design and Patient Engagement” and will focus on engaging older adults in the design of technology.

Chen AT (co-first author), Backonja U (co-first author), Cato K. Integrating health disparities content into health informatics courses: a cross-sectional survey study and recommendations. JAMIA Open. 2023;6(1):ooac101.

At the AMIA Informatics Summit 2023, the Clinical Research in Informatics (CRI) stream Year-in-Review named four papers published by AMIA members as the Notable papers on Social Determinants of Health (SDoH) methods. Two of the papers were co-authored by BIME PhD students, alumni, and former faculty and in conjunction with work in the National COVID Cohort Collaborative (N3C):

• Phuong J, Zampino E, Dobbins N, Espinoza J, Meeker D, Spratt H, Madlock-Brown C, Weiskopf NG, Wilcox A. Extracting Patient-level Social Determinants of Health into the OMOP Common Data Model. InAMIA Annual Symposium Proceedings 2021 (Vol. 2021, p. 989). American Medical Informatics Association.
• Teng A, Wilcox A. Simplified data science approach to extract social and behavioural determinants: A retrospective chart review. BMJ open. 2022 Jan 1;12(1):e048397.

Chen, A. T., Huey, J., Coe, S., Kaganovsky, J., Malouf, E. A., Evans, H. D., Daker, J., Harper, E., Fordiani, O., Lowe, E. E., Oldroyd, C., Price, A., Roth, K., Stoddard, J., Crandell, J. N., Shirts, B. H. (accepted). Extending cascade screening using genealogy, direct-to-consumer ancestry genetics, and social media – the ConnectMyVariant exploratory pilot study. JMIR Cancer.

Rao, N. D., Kaganovsky, J., Malouf, E., Coe, S., Huey, J., Tsinajinne, D., Hassan, S. King, K., Fullerton, S. M.,
Chen, A. T., Shirts, B. H. (accepted). Diagnostic yield of genetic screening in a diverse, community-ascertained cohort. Genome Medicine.

Annie Chen gave a presentation on March 10, 2023, at the Luddy School of Informatics, Computing, and Engineering, Indiana University Bloomington, entitled, “Collaboratively interpreting life experiences through visual and textual media: Reflections from digital humanities and health-related research.”

ANNOUNCEMENTS
George Demiris, PhD, FACMI, the Mary Alice Bennett University Professor and Penn Integrates Knowledge University Professor, has been appointed Penn Nursing’s next Associate Dean for Research and Innovation. Penn Nursing Dean Antonia M. Villarruel said “Dr. Demiris’ research and innovation expertise, curiosity, and commitment to social justice is impactful and it will be transformational in his new role at our School.” This appointment will begin on June 1, 2023.

New For All UW Researchers: Covidence, Evidence Synthesis Tool
UW Health Sciences Library has announced the implementation of an institutional license for Covidence, a popular online platform for evidence synthesis projects, including systematic reviews, meta-analyses, and more. Available to all UW users.

The recording from our recent CLIME Conversation Café featuring Spokane Foundations Educators is now available!

CLIME has developed a series of “CLIME Conclusions!” to summarize complex medical and health professions education topics in one page! Check out “Designing Learning Experiences.”

CLIME has developed a series of “CLIME Clips!” to offer succinct actionable teaching tips for medical and health professions educators. Check out the rest of our “CLIME Clips!”

Karin Verspoor Presentation
On 3/16/2023, Karin Verspoor presented “ChatGPT: What it is, what it isn’t, and what you need to know.” The presentation is posted here for you to view and the slides can be viewed here.

Abstract: ChatGPT is a conversational AI tool from Open AI based on natural language generation that has taken the world by storm, due to its capacity to produce text that is fluent and convincing in response to open-ended prompts. In this talk, I aim to “demystify” ChatGPT by describing (conceptually) how it works and discussing what we do and don’t understand about it. I will show some examples of things it does very well, and things that it does less well. I will describe some concerns that have been raised about ChatGPT, and discuss unintended consequences already observed from broad adoption of the tool. A key consideration for potential safety-critical applications such as in clinical medicine is trust in the correctness of the information such a tool provides. We cannot reject or avoid ongoing AI innovation. It is therefore imperative that we engage with it with our eyes open, and work towards systems that support and benefit human activities, and mitigate potential harm.
Speaker Bio: Professor Karin Verspoor is Executive Dean of the School of Computing Technologies at RMIT University in Melbourne, Australia. She is a Fellow of the Australasian Institute of Digital Health, a 2021 “Brilliant Woman in Digital Health”, and was selected as a finalist in the Women in AI Australia/New Zealand Awards 2022 for “AI in Innovation”. Karin is passionate about using artificial intelligence to enable biological discovery and clinical decision support from data. Her work has a specific emphasis on the use of natural language processing to transform unstructured data in biomedicine into actionable information. Karin held previous posts as Director of Health Technologies and Deputy Head of the School of Computing and Information Systems at the University of Melbourne, as the Scientific Director of Health and Life Sciences at NICTA Victoria Research Laboratory, at the University of Colorado School of Medicine, and at Los Alamos National Laboratory. She also spent 5 years in tech start-ups during the US Tech bubble, where she helped design an early artificial intelligence system. Karin received a BA with a double major in Computer Science and Cognitive Sciences from Rice University in Houston, TX, USA, and completed both a MSc and PhD in Cognitive Science and Natural Language at the University of Edinburgh, UK.

March 13 – March 17, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
*No class on March 23*
Class will resume on March 30^th, 2023. The presenter will be Ari Pollack, MD, MSIM. More details next week!

PUBLICATIONS & PRESENTATIONS
Bekemeier B, Heitkemper E, Backonja U, Whitman G, Schultz M, Jiang Y, Baquero B, Turner AM. Rural public health data challenges during the COVID-19 pandemic: The case for building better systems ahead of a public health crisis. Journal of Public Health Management & Practice. [ePub ahead of print]. doi: 10.1097/PHH.0000000000001726.

Bhattacharya A, Backonja U, Le A, Antony R, Si YJ, Lee JH. Understanding the Influence of Music on People’s Mental Health Through Dynamic Music Engagement Model. iConference 2023. Barcelona, Spain. March 2023.

ANNOUNCEMENTS
Congratulations to Xiruo Ding for the selection of his paper, Augmenting aer2vec: Enriching distributed representations of adverse event report data with orthographic and lexical information, as one of the IMIA Yearbook best NLP papers of 2022: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0042-1742548

Thomas Payne, MD, FACMI, was featured on KUOW discussing the growing use of electronic health records by large corporations. Click here for the story.

Uba Backonja led a team at MITRE to develop journey maps for HRSA’s Optimizing Virtual Care program to help health centers support virtual care equity. The journey maps, a guide, references, and resources can be found here.

The recording from our recent CLIME Grand Rounds featuring Justin Bullock is now available!

March 6 – March 10, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590

*No class on March 16 and March 23*
 Class will resume on March 30^th, 2023.

PUBLICATIONS & PRESENTATIONS
Andrea Hartzler and Janice Sabin were interviewed for a feature article in Science about their work on implicit bias!

The Science article “Do no unconscious harm” features the life’s work of Janice Sabin and work of the UnBIASED project led by Andrea Hartzler with Janice Sabin, Wanda Pratt, Brian Wood, Nadir Weibel. Current UW student contributors to UnBIASED include Reggie Casanova-Perez, Emily Bascom, Connie Yang, Amrit Bhat, Nikhil Kashyap, Anagha Bandaru, Anuhya Bhagavatula, Juhi Choubey, Shrusti Ghela, Niyat Effrem, Pooja Thoral, and JP Lopez.

ANNOUNCEMENTS
CLIME has developed a series of “CLIME Conclusions!” to summarize complex medical and health professions education topics in one page! Check out “Intro to Cognitive Science.”

February 27 – March 3, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Presenter: Patrick Mathias, MD, PhD
Thursday, March 9^th – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Title: Using Clinical Decision Support to Nudge the Way to Improved Laboratory Stewardship
Abstract: Clinical laboratory tests are among the highest volume procedures in routine health care delivery, and variation in test ordering patterns between practitioners can be significant. Laboratory stewardship aims to maximize the value of lab testing by identifying opportunities to both decrease unnecessary use as well as identify underutilized tests that can lead to better outcomes. With almost all lab tests now ordered through electronic health records, there are numerous opportunities to use EHR tools to guide the selection of optimal testing. In this talk, we will review examples of traditional interruptive decision support, non-interruptive approaches to steer ordering, feedback to ordering providers, and combinations of these approaches to promote improved stewardship. Finally we will consider how investments in decision support might be guided to best use limited health care informatics resources.
Presenter Bio: Patrick Mathias, MD, PhD, is an Assistant Professor who serves as the Vice Chair of Clinical Operations and an Associate Medical Director of the Informatics division in the Department of Laboratory Medicine and Pathology at the University of Washington School of Medicine. He is also the Medical Director of Point of Care Testing for Airlift Northwest. He is board certified in Clinical Pathology and Clinical Informatics. Dr. Mathias’s interests include improving clinical information systems to improve the ordering and interpretation of laboratory tests and applying analytics to improve diagnosis and operations as well as extend the lab’s impact on clinical care.

UPCOMING GENERAL EXAM
Title: Leveraging multi-modal models to detect osteoporotic compression fractures
Student: Brian Chang

• March 7 10-11:30 am
• Location: South Lake Union, 750 Republican, Building E, Room E130
• Zoom link: https://washington.zoom.us/j/93719523879

Abstract: Osteoporotic compression fractures (OCFs) are a public health concern and multi-modal machine learning (ML) models of electronic health record (EHR) data, including structured data, text, and images, offer the potential to improve detection and subsequent osteoporosis management. OCFs are an early biomarker of osteoporosis, a chronic disease that affects roughly 10 million Americans aged ≥50 years. However, they remain under-diagnosed and under-reported by radiologists and are associated with lower quality of life and increased mortality and morbidity. Although osteoporosis screening is evidence-based, it remains grossly underutilized. In this project, our overall goal is to study different elements of an automated tool to detect OCFs, leveraging clinical notes, radiographs, and structured EHR data, retrospectively. We will 1) train transformer models and develop an ensemble model to extract clinical findings of interest from unstructured text 2) develop an end-to-end automated imaging analysis pipeline, and 3) leverage independent text mining and imaging analysis models in a multi-modal model, which will be tested and validated in detecting OCFs.

PUBLICATIONS & PRESENTATIONS
C.L. Nau, S.E. Wang, L.A. Viveros, A.M. Rich, M. Sidell, A. Padilla, J. Briganti, C. Gandhi, J. Ngo, T. Dao, P. Vila, G. Luo, and H. Nguyen. An Intuitive Introduction to Predictive Models for Palliative Care: How Smart is Artificial Intelligence? National Symposium for Academic Palliative Care Education and Research, Long Beach, CA, Mar. 2023.

Members of the UnBIASED research have been invited to present their work at the AI Showcase at the AMIA upcoming Summits meeting on Tuesday March 14^th 1:30-3pm at AI Showcase – Session 2: Stage 1
Bedmutha M, Sladek K, Bascom E, Andreui A, Sabin J, Pratt W, Wood B, Hartzler AL, Weibel N. “Extracting Meaningful Social Signals from Patient-Provider Interactions”. Presentation to appear at AMIA Summits 2023, Seattle, WA.

As part of an invited panel,  Anne Turner will be presenting on Decision-making and Alzheimer’s Research project at the American Association for the Advancement of Science (AAAS) Annual Meeting (https://meetings.aaas.org/).  The talk entitled, “Strategies for engaging older adults in decision-making: DMAR”, will be presented on Friday March 3^rd at 1pm (ET) in Washington DC.

ANNOUNCEMENTS
Jim Phuong was part of the National COVID Cohort Collaborative (N3C) team participating in the National Institute of Health DataWorks! Challenge (https://www.herox.com/dataworks). This challenge focuses on reused or shared data to further biological and/or biomedical research. The N3C team was announced as one of the two grand prize winners ($100,000)!

Serena Xie, Weichao Yuwen, and Andrea Hartzler were awarded a Tier 1 Pilot Research Grant from the Population Health Initiative: “Understanding the needs of families caring for Chinese American older adults and opportunities for digital health tools to promote health equity.”

UW Institute for Medical Data Science (IMDS) Featured in GeekWire
The UW Institute was announced at the 2023 Medical Data Science Symposium. The Symposium’s keynote speaker, Atul Butte, along with 20+ other speakers, highlighted uses of AI and data science in Medicine and Human Health. The IMDS is coalescing the campus community and creating new collaborations across clinical and computational sciences.

CLIME has developed a series of “CLIME Clips!” to offer succinct actionable teaching tips for medical and health professions educators. Check out the rest of our “CLIME Clips!”

February 20 – February 24, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Presenter: Annie Chen, MSIS, PhD & Sharon Wong
Thursday, March 2^nd – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]

Title: Leveraging the Everyday in Digital Health Interventions
Abstract: Narratives are a powerful way in which we make sense of life. Many of us cope with health challenges, and we are increasingly witnessing the development of behavioral health interventions intended to empower us to meet these challenges more effectively. However, with chronic conditions, there may be barriers that impede successful behavioral change. Successfully addressing these barriers may require more intimate knowledge of complexities and targeted solutions than we currently have. In this talk, we present two examples of research in which we incorporate the power of narrative in interventions and research to address contextualized health management needs. The first example is an exploratory study employing multiple methods (e.g., natural language processing, content analysis) to perform analysis of two narrative data sources, social media and questionnaire data, with the overarching goal of identifying stigma phenotypes and leverage points for future stigma reduction interventions. The second example involves the iterative development of an online problem-solving intervention for older adults. Though both examples employ narrative, they do so in different ways. The presentation will present an overview and reflection on the affordances and challenges of leveraging narrative to facilitate health behavior change.

Presenter Bios:
Annie T. Chen is Associate Professor of Biomedical Informatics at University of Washington (UW) School of Medicine. Her research interests include information behavior, psychosocial and communicative processes in online spaces, and supporting human interactions with digital technologies; and leverages data analytic approaches and stakeholder-engaged approaches. Dr. Chen has also been active in the organization of the workshop, Visual Analytics in Healthcare, which is held at the annual meeting of the American Medical Informatics Association (AMIA) and IEEE VIS in alternate years.

Sharon Wong is a second year Master’s student in Biomedical and Health Informatics at UW School of Medicine. She currently works with Dr. Chen on the stigma phenotypes research as well as an online problem-solving intervention, where she conducts user-centered design research toward the development of a participant insight dashboard. Outside of BIME, she also assists with speech perception and auditory processing research in infants using electroencephalography (EEG) methods through the UW Department of Otolaryngology-Head and Neck Surgery.

ANNOUNCEMENTS
New Institute for Medical Data Science

Please see the story about the Institute for Medical Data Science in The Huddle featuring our own Sean Mooney.

CLIME has developed a series of “CLIME Conclusions!” to summarize complex medical and health professions education topics in one page! Check out “Intro to Adult Learning Theory.”

February 13 – February 17, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Presenter: Laura Wiley, PhD
Thursday, February 23^rd – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]

Title: Developing an Equitable Learning Health System

PUBLICATIONS & PRESENTATIONS
Lauren Snyder, Rebecca Hazen, Amanda Hall. What is the new future of work for user experience research practice? Assessing human computer interaction research practice during the COVID-19 pandemic and beyond. HCI International Conference 2023.

Kahn NF, Anan YH, Bocek KM, Christakis DA, Richardson LP, Pratt W, Sequeira GM. Understanding Transgender and Gender-Diverse Youth’s Experiences Receiving Care via Telemedicine: Qualitative Interview Study. JMIR Pediatr Parent 2023;6:e42378. doi: 10.2196/42378 PMID: 36745775

Dzara K, Khan A, and Berkowitz LR. 2022. “Vice Chairs for Education as Servant Leaders: A Convergent Mixed-Methods Study.” Research and Development in Medical Education. 11:23.
https://rdme.tbzmed.ac.ir/Article/rdme-33077

ANNOUNCEMENTS

Medical Education Research Certificate Session

Purpose: CLIME is again offering the Association of American Medical Colleges (AAMC) Medical Education Research Certificate (MERC). To receive the certificate participants must complete 6 half day sessions.

First Session: The first session will take place via Zoom on the date and time below. The session is hands-on and will require active participation.

Friday, May 5, 2023 | 9:00am – 12:00pm (PT) | Zoom Formulating Research Questions and Designing Studies Facilitator: Jean Bailey, PhD Associate Dean for Faculty Development, Virginia Commonwealth University

Registration: Space is limited to the first 25 registrants. This opportunity is available for UW affiliated faculty, staff, and students throughout the WWAMI Region. Register: https://uw.cloud-cme.com/course/courseoverview?P=29&EID=8557

Learn More about MERC: https://www.aamc.org/about-us/mission-areas/medical-education/meded-research-certificate-program

Email clime@uw.edu with any questions

February 6 – February 10, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Presenter: Sarah Stansfield, PhD MPH
Thursday, February 16^th – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Title: Estimating benefits of using on-demand oral prep by MSM: A comparative modeling study of the US and Thailand

Abstract: Daily and on-demand pre-exposure prophylaxis (PrEP) are effective at preventing HIV acquisition among men who have sex with men (MSM), but only daily PrEP is approved in the US. On-demand PrEP may improve uptake and adherence. We identify sub-groups of MSM who would benefit from on-demand PrEP and determine effectiveness achieved if individuals used their optimal regimens.
Using data from the HPTN 067 study (study period 2012–2014), we created an individual-based stochastic model of HIV risk in two synthetic MSM populations with parameters separately estimated using data from Harlem, US, and Bangkok, Thailand and found that simulated on-demand PrEP was optimal for approximately one-third of MSM. It was assigned mainly to those with low daily PrEP adherence.
On-demand PrEP could benefit many MSM by increasing effectiveness or decreasing pill burden with similar effectiveness. On-demand PrEP may be an effective alternative to daily PrEP for individuals with difficulty taking daily PrEP consistently. Results were similar for Harlem and Bangkok, indicating that these conclusions were robust in populations with different overall adherence levels and may inform future public-health policies.

Presenter bio: Dr. Sarah Stansfield is a post-doctoral research fellow at the Fred Hutchinson Cancer Center. She holds a PhD in Anthropology and an MPH in Epidemiology from the University of Washington where she focused on questions about HIV virulence and virulence evolution using mathematical modeling. Her current work examines the impacts of new PrEP regimens, including on-demand PrEP and long acting injectable (LAI) PrEP, on HIV in men who have sex with men (MSM) and in heterosexual populations in South Africa.

ANNOUNCEMENTS
CHI 2023 Workshop
Interested in remote/hybrid work and care (of selves, communities, or environment) in HCI? Submit to our #CHI2023 workshop “The Future of Hybrid Care and Wellbeing in HCI”, co-organized by @_karthik_bhat, @azraism, @mandikhall, @helena_mentis, @avakaya_annam, @almostjohnvines, and @nehakumar!
Apply here by Feb 23: https://sites.google.com/view/hybrid-care-wellbeing-chi2023

CLIME Grand Rounds
How Competency-Based Education is Changing Training Everywhere
Jason Frank, MD, Professor of Emergency Medicine, University of Ottawa
March 28^th, 2023
9:00am – 10:00am (PT)
Zoom (Online)
Register here: https://uw.cloud-cme.com/course/courseoverview?P=0&EID=8497

January 30 – February 3, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Presenter: Brian Hur, DVM, PhD
Thursday, February 9^th – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Title: Making sense of clinical notes: How NLP can help improve antibiotic prescribing

Abstract: Clinical records are a rich source of information in veterinary medicine, but the fragmentation of data across different clinics presents a major challenge to population-level analysis. Natural language processing (NLP) can help overcome this obstacle and provide a more comprehensive understanding of antimicrobial usage patterns. Utilizing data from VetCompass Australia and NLP techniques, studies have successfully identified antimicrobial usage patterns in companion animal practices. The automation of prescribing habit extraction through NLP has demonstrated promise in early studies and is being implemented as part of a larger antimicrobial stewardship campaign. This research highlights the critical role NLP can play in improving antimicrobial stewardship in veterinary medicine and its potential for application in human medicine.
Presenter Bio: Dr. Brian Hur is currently a postdoctoral fellow of Biomedical Informatics and Medical Education at the University of Washington.  He holds a Doctor of Veterinary Medicine degree from Washington State University and a PhD in Natural Language Processing and Epidemiology from the University of Melbourne where he focused on developing and improving NLP methods to extract data from free text clinical records to support antimicrobial stewardship efforts in Australia. In addition to research, he has a background in veterinary medicine, treating small and exotic animals, including time spent at the Turtle Rehabilitation Center on the Great Barrier Reef. He has also gained valuable experience as an engineer, working for companies such as Microsoft and Boeing, and contributing to a number of startups. His unique blend of skills and experiences make him a valuable asset in the field of Biomedical Informatics and Engineering.

PUBLICATIONS & PRESENTATIONS
Gina Sequeira, Nicole Kahn, Keven Bocek, Taraneh Shafii, Peter Asante, Dimitri Christakis, Wanda Pratt, Laura Richardson. Pediatric Primary Care Providers’ Perspectives on Telehealth Platforms to Support Care for Transgender and Gender-Diverse Youths: Exploratory Qualitative Study. Journal of Medical Internet Research (JMIR) Hum Factors 2023;10:e39118. doi: 10.2196/39118 PMID: 36719714

Anastasia Schaadhardt, Chris Fu, Cory Pratt, Wanda Pratt. “Laughing so I Don’t Cry”: How TikTok Users Employ Humor and Compassion to Connect Around Psychiatric Hospitalization. Proceedings of the 2023 ACM Conference on Human Factors in Computing Systems (CHI 2023)

Yan Zhang, Melissa G. Ocepek, and Annie T. Chen co-edited a special issue for Library & Information Science Research entitled, “Research Methods in Information Behavior/Practice Research.” Read more about the special issue here:

 Chen, A. T., Ocepek, M. G., Zhang, Y. (2023). Guest editorial: Research methods in information behavior research. Library & Information Science Research, 45(1), 101221. https://doi.org/10.1016/j.lisr.2022.101221

Han, S., Teng, A. K., Lin, S.-Y., Demiris, G., Zaslavsky, O., & Chen, A. T. (accepted). Examining engagement and usability in an online discussion platform for older adults: Findings from pilot studies. Computers, Informatics, Nursing. DOI: 10.1097/CIN.0000000000001001

Members (see below) of the “UnBIASED project” research team, a collaboration between UW and UCSD researchers, have been invited to present work at the AMIA 2023 AI Evaluation Showcase! This presentation is the first stage of the three-stage showcase. Stage 1 focuses on technical performance studies that will be presented at AMIA Summits in Seattle March 13-16.
Bedmutha M, Sladek K, Bascom E, Andrieu A, Sabin J, Pratt W, Wood B, Hartzler AL, Weibel N. Extracting meaningful social signals from patient-provider interactions. To appear at 2023 AMIA Summits.

Dahal, Arati; Kardonsky, Kim; Cunningham, Matthew; Evans, David V.; Keys, Toby. The Effect of Rural Underserved Opportunities Program Participation on Medical Graduates’ Decision to Work in Rural Areas. Academic Medicine ():10.1097/ACM.0000000000005162, February 01, 2023. | DOI: 10.1097/ACM.0000000000005162. https://journals.lww.com/academicmedicine/Abstract/9900/The_Effect_of_Rural_Underserved_Opportunities.349.aspx

Wanda Pratt is an invited panelist for the National Library of Medicine Workshop “Meeting the Needs of Diverse Populations Through Tailored Personal Health Informatics” on February 22, 2023.

Janice Sabin has been invited by Patricia Cuff, Director, National Academies Global Forum on Innovation in Health Professional Education, to participate in a Working Group to explore issues related to Maternal Health Disparities. The focus is on education and workforce development and various forms of bias.

ANNOUNCEMENTS
AMIA DEI Communications Cochair Selected
Shefali Haldar (’19) was selected as the new Co-chair of the Communications Subcommittee. Shefali has served as a member of the committee and enthusiastically supported the subcommittee’s efforts to bring the Inclusive Language and Context Style Guidelines to fruition.

This year, the DEI subcommittee will roll out the guidelines at each AMIA meeting, informing and educating thousands of members, authors and reviewers about the importance of inclusive language. It’s a new standard for AMIA and Shefali will join Hu Huang, current co-chair, in supporting the entire committee’s work.

January 23 – January 27, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Presenter: Dr. Daniel Capurro, PhD
Thursday, February 2^nd – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Title: Digital Overdiagnosis
Abstract: Overdiagnosis happens when someone is found to have abnormalities that meet the existing diagnostic criteria for diseases or risk factors, but would have never experienced any consequences if left undiagnosed. Dr. Capurro will present an overview of overdiagnosis and how the growing number of digital diagnostic algorithms, including ML, might affect its frequency and longer-term consequences. Overdiagnosis has been extensively recognized for traditional diagnostic tests but is still understudied for digital diagnostic algorithms. The ability to predict future appearance of abnormalities and diseases is making the situation even more complex. Dr. Capurro will discuss his current research in this domain, and existing opportunities and challenges.
Presenter Bio: Dr. Capurro is an Associate Professor in the School of Computing and Information Systems and Deputy-Director of the Centre for the Digital Transformation of Health in the Faculty of Medicine, Dentistry and Health Sciences at the University of Melbourne. He is affiliate faculty in the Department of Biomedical Informatics and Medical Education at the University of Washington. Daniel is the deputy editor for NPJ Digital Medicine and member of the editorial boards of the Journal of Biomedical Informatics and Informatics for health and Social Care. Before moving to Australia, Dr. Capurro served as the Chief Medical Information Officer at Chile’s Catholic University academic healthcare network and founded the Chilean National Centre for Health information Systems (www.cens.cl). Dr. Capurro is a Medical Doctor, General Internist, and completed his PhD at the University of Washington under the supervision of Dr. Peter Tarczy-Hornoch.

PUBLICATIONS & PRESENTATIONS
Zhou S, Lybarger K, Yetisgen M, Ostendorf M. Generalizing through Forgetting — Domain Generalization for Symptom Event Extraction in Clinical Notes. arxiv link (Accepted 2023 AMIA Summit)

Lybarger K, Yetisgen M, Uzuner O. The 2022 n2c2/UW Shared Task on Extracting Social Determinants of Health. arxiv link (Accepted Journal of American Medical Informatics Association)

ANNOUNCEMENTS
2023 Call for CLIME Small Grant Proposals

CLIME’s mission is to create a diverse, inclusive, and welcoming community that works together to optimize teaching skills, foster educator career development, and support educational scholarship.

In keeping with our mission, CLIME is pleased to announce a funding opportunity for UW School of Medicine Faculty who are interested in pursuing education scholarship. The goal of this funding opportunity is to provide faculty with opportunities to develop innovative health professions education scholarship, including the scholarship of discovery, integration, application, and teaching. By providing ongoing support to these UW activities, we hope to develop and support a community of education scholars.

We are particularly interested in funding projects that include junior faculty members. While all applications must include a UW School of Medicine faculty member on the project, we strongly encourage interprofessional submissions. Priority will be given to projects that are innovative, enhance the quality of research in health sciences education, and promote the application of scholarship to practice.

CLIME has a total of $20,000 available for funding during this grant cycle. Awards are capped at $5,000. Travel and conference fees are not supported. We seek to distribute awards across the five-state, WWAMI region. Application Deadline is March 31, 2023, 11:59pm (PST)

Full Call for Applications

CLIME Grand Rounds
The Learning Environment is Key for Equitable Assessment
Justin Bullock, MD, MPH, Fellow in Nephrology, University of Washington School of Medicine

March 3, 2023
12:00pm – 1:00pm (PT)
Zoom (Online)

Register here: https://uw.cloud-cme.com/course/courseoverview?P=0&EID=8505

January 16 – January 20, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Due to ongoing changes in the personal schedules of presenters for BIME 590 there will be no presenter for BIME 590 on Thursday Jan 26^th.

PUBLICATIONS & PRESENTATIONS
J.L. Renslo, B. Chang, Q. Dong, D.R. Haynor, S.K. Johnston, G. Luo, J. Perry, S. Shubber, N.E. Lane, L. Marshall, J.G. Jarvik, and N.M. Cross. U-Net for Spine Segmentation – Towards Automated Fracture Detection. Annual Meeting of the American Society of Neuroradiology (ASNR’23), Chicago, IL, Apr. 29 – May 3, 2023.

Dong, G. Luo, N.E. Lane, L. Lui, L.M. Marshall, S.K. Johnston, H. Dabbous, M. O’Reilly, K.F. Linnau, J. Perry, D. Haynor, J.G. Jarvik, B. Chang, J. Renslo, and N.M. Cross. Generalizability of Deep Learning Classification of Spinal Osteoporotic Compression Fractures on Radiographs Using an Adaptation of the Modified-2 Algorithm-Based Qualitative Criteria. Annual Meeting of the American Society of Neuroradiology (ASNR’23), Chicago, IL, Apr. 29 – May 3,2023.

Zhang, S.B. Zeliadt, M. Walker, M.R. Levitt, B. Ng, and G. Luo. Assessing the Robustness of a Machine Learning Model for Predicting Asthma Hospital Encounters during the COVID-19 Pandemic. American Thoracic Society (ATS) International Conference (ATS’23), Washington, DC, May, 2023.

ANNOUNCEMENTS
Student Led Small Groups
Charlie Charman, MD, Paula Silha, MD, and Mike Stephens, MD, Spokane Foundations Educators
Please join us for a CLIME Conversation Café to highlight student led small groups with active learning opportunities.
February 24, 2023
12:00pm – 1:00pm (PT)
Zoom (Online)
Register: https://uw.cloud-cme.com/course/courseoverview?P=0&EID=8525

January 9 – January 13, 2023

UPCOMING LECTURES AND SEMINARS

BIME 590
Presenter: Dr. Thomas Wetter, PhD
Thursday, January 19^th – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Title: Personal Health Informatics services and the values they create

Abstract: We define Personal Health Informatics (PersHI) as the methodology of services that enable citizens to use ICT to safely play an active role in their health care. Compared to Consumer Health Informatics, PersHI not only looks at individuals health hazards and their mitigation but also at effects in society at large. The presentation tries a wide perspective on values that can be achieved through PersHI services. We distinguish four major types of values.
First, clinical effectiveness in the veins of the approval process for new treatments. This is typically shown through controlled experiments such as Randomized Controlled Trials (RCTs) and delivers an improved clinical outcome. Second, insights that emerge without advance planning as discoveries in data volunteered by citizens and later purposefully aggregated. The aggregation may show some meaningfully association or effect. Medication adverse effects coincidentally reported by several patients in self-support groups or social media are an example. Third, we report about changes in mindset that are achieved through PersHI services. This can be acquired knowledge, changed emotions or attitudes and the like and may culminate in changed behaviors. New knowledge may be learned or the propensity for (healthy) behavior may evolve in citizens. Such individual mindsets develop privately. By contrast, the fourth value, group power is achieved though group members using social media to get organized and to solicit public attention, permissions, or resources towards attenuation of a medical problem of the group members. Access to restricted chemicals for presumably therapeutic purposes is an example.
Positive and negative examples demonstrate the subtlety of the field: RCTs with clearly significant effects and others that were terminated prematurely due to lack of participation and subject retention; knowledge gained with no behavioral consequences and behavior change without notable knowledge increase; and pressure groups with true benefits for their clientele but others that lead to the waste of resources because the therapy advocated for was futile. The presentation is based on my chapter 20 of the recent book: P.S. Hsueh, T. Wetter, and X.K. Zhu, Editors. Personal Health Informatics: Patient Participation in Precision Health. Cham (Springer) 2022. ISBN 978-3-031-07695-4, ISBN 978-3-031-07696-1 (eBook)

Presenter Bio: Prof. (em.) Dr. Thomas Wetter is a Medical Informatics scholar with twelve years of experience in industry research and 30 years of experience in academic research and teaching in Biomedicine. A graduate and PhD in Mathematics from Aachen Technical University he worked most of his career on applying formal methods to biomedical problems. After eight years of physiological research in Aachen he joined the IBM Heidelberg Scientific Center. Here he researched and published on Human Computer Interface design, Artificial Intelligence, Natural Language Processing, Voice Recognition, and Software Quality. In 1997 he was appointed a full professor for Medical Informatics at Heidelberg University. Besides teaching in the curricula Medical Informatics and Medicine his research interests were in clinical applications of Voice Recognition and Artificial Intelligence and later in Consumer Health Informatics. In the years till 2018 his assignments included the management of a CME academy, the Heidelberg part of an international student exchange program (IPHIE), associate editor of the International Journal of Medical Informatics, and deputy chair and later chair of the IMIA WG Consumer Health Informatics.
Besides various articles in scientific journals he is the editor of conference proceedings in artificial intelligence and author of the Springer 2016 textbook “Consumer Health Informatics. New Services, Roles, and Responsibilities” and co-editor of the Springer 2022 volume Personal Health Informatics: Patient Participation in Precision Health. During his active time Dr. Wetter spent sabbaticals at the University of Utah and the University of Washington. After his retirement he was engaged by Ben-Gurion-University of the Negev in Be’er Sheva, Israel to help develop a curriculum Medical Informatics.

PUBLICATIONS & PRESENTATIONS
Zhao LP, Cohen S, Zhao M, Madeleine M, Payne TH, Lybrand TP, Geraghty DE, Jerome KR, Corey L.   Predicting SARS-CoV-2 recombinants and novel mutations using a haplotype-based artificial intelligence.  JAMA Network Open.  Accepted for publication.

Jujjavarapu, C., Suri, P., Pejaver, V., Friedly, J., Gold, LS., Meier, E., Cohen T., Mooney, SD., Heagerty PJ., Jarvik, JG. Predicting decompression surgery by applying multimodal deep learning to patients’ structured and unstructured health data. BMC Med Inform Decis Mak 23, 2 (2023). https://doi.org/10.1186/s12911-022-02096-x

ANNOUNCEMENTS
Janice Sabin has been invited to give a one-hour guest lecture and follow up interactive workshop at the Paediatrics Skåne University Hospital, Lund, Sweden, March 23, 2023, (Zoom). Sweden has experienced an influx of immigrants in recent years and accompanying racism and bias in healthcare, but with little education on the topic for healthcare providers.

Small Group Facilitator Webinar Series
Learn to Facilitate Your Group and Maximize Student Learning
Developed by Educators at Michigan State University
*This webinar series is provided by CLIME to all UW affiliated faculty, staff, and students 

• October 19th:Building a Safe Learning Environment: Getting to Know Your Students and Build Relationships Quickly
• October 26th: Building a Safe Learning Environment: Setting Clear Expectations
• December 7th: Noticing and Encouraging Small Group Participation
• December 21st:Understanding and Drawing Out Introverted Learners
• February 1st:Exercising the Mind and Body to Maximize Student Learning
• February 22nd: Clinical Debriefing

Register to obtain access to the webinars as they are released

January 2 – January 6, 2023

UPCOMING LECTURES AND SEMINARS
BIME 590
Presenter: Thomas Payne, MD, FACP, FACMI, FAMIA
Thursday, January 12^th – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Title: The real world of electronic health records:  A brief tour of how they are used in 2023

Abstract: What are electronic health records really like?  Despite our progress and their broad adoption, the reality of electronic health records as used today is very different than the ideal, and different from what many people who do not use them every day envision them to be.   In this talk, illustrated with examples, I’ll focus on documentation, including hospital progress notes and clinic notes, and also discuss clinical decision support, interoperability, machine learning, how clinicians write notes, and where in the EHR key communications can be found.  (Hint:  It is not always in notes.)  This presentation will be helpful to those in bioinformatics who use data derived from EHRs and those working to improve them.
Presenter Bio: Thomas Payne is a primary care internist, Professor of Medicine and of Biomedical Informatics, and for 20 years served as Medical Director for Information Technology Services at University of Washington Medicine. He is attending physician at UW Medical Center and Harborview Medical Center in both inpatient and outpatient care.  He is past Board Chair of the American Medical Informatics Association (AMIA). He chaired the AMIA EHR 2020 Task Force and testified before the US Senate HELP Committee on its contents.  He is on the faculty of the AMIA Clinical Informatics Board Review course, edits a textbook on clinical computing systems and is author of over 100 articles in informatics.  He is Senior Editor of Applied Clinical Informatics and on the editorial board of JAMIA and JAMIA Open.
Dr. Payne’s research is in EHR contents, including notes, and how they can be used to measure illness acuity, symptom patterns, and risks for heritable cancer.  He graduated from Stanford and received his medical degree from the University of Washington. He completed his residency in Medicine at University of Colorado and an NLM fellowship in Medical Information Science at Massachusetts General Hospital and Harvard School of Public Health.

PUBLICATIONS & PRESENTATIONS
Xie SJ, Kapos FP, Mooney SJ, Mooney S, Stephens KA, Hartzler AL, Pratap A. Geospatial divide in real-world EHR data: Analytical workflow to infer regional biases and potential impact on health equity AMIA Summits 2023.

Sangameswaran S, Cano-Calhoun C, Ton D, Xie SJ, Keppel G, Pearson J, Many G, Bauman D, Idziorek K, Kapos FP, Mooney S, Stephens K, Pratap A, Chen C, Hartzler AL. Needs and preferences for community-tailored physical activity interventions for people with obesity in socially vulnerable neighborhoods. AMIA Summits 2023.

Karthik S. Bhat, Amanda Hall, Tiffany Kuo, and Neha Kumar. (2023). “We are half-doctors”: Family Caregivers as Boundary Actors in Chronic Care Management. Proc. ACM Hum.-Comput. Interact. CSCW1. (forthcoming in 2023).

ANNOUNCEMENTS
Nick Reid has joined the JAMIA 2023 Student Editorial Board. Congrats!

CLIME has developed a series of “CLIME Conclusions!” to summarize complex medical and health professions education topics in one page! Check out “Publishing Educational Scholarship.”

December 26 – December 29, 2022

UPCOMING LECTURES AND SEMINARS
BIME 590: See you next week!
Presenter: Wen-Wai Yim, PhD, Senior Applied Scientist, Microsoft Health and Life Sciences
Thursday, January 5^th – 11-11:50 am
850 Republican Street, Building C, Room 123 A/B
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Title: Understanding Medical Language and Semantics for Ambient Clinical Note Generation
Abstract: Clinical note generation from doctor-patient conversation requires complex natural language processing, including speech processing such as speech-to-text, speaker diarization, and speaker role labeling; and afterwards paraphrasing, summarizing over multiple statements and question-answers. The text generation is particularly challenging given the specialized nature of medical language and diverse semi-structured variations in clinical notes. In this talk, I will discuss the interesting nature of medical language and semantics in this problem space; as well as describe state of the art research in ambient clinical note generation, controlled generation, evaluation, and dataset creation.
Presenter Bio: Wen-wai Yim is a Senior Applied Scientist at Microsoft Health and Life Sciences working on clinical note generation from doctor-patient visit ambient conversations. She received a PhD in Biomedical Informatics at the University of Washington, where she worked on clinical information extraction and text prediction. Afterwards, she spent two years as a postdoctoral scholar at Stanford University working with electronic medical records; before leaving for industry where she has led AI efforts in note generation from medical conversation at start-ups. She has published scientific articles in the biomedical NLP space and she is reviewer for major conferences such as ACL, EMNLP; and biomedical conferences and journals such as AMIA and Journal of Biomedical Informatics. Her interests includes leveraging linguistic resources for NLP, studying semantic variations, controllable generation, and natural language evaluation.

PUBLICATIONS & PRESENTATIONS
Ariel S. Frey-Vogel, Kevin Ching, Kristina Dzara, Leah Mallory. The Acceptability of Avatar Patients for Teaching and Assessing Pediatric Residents in Communicating Medical Ambiguity. Journal of Graduate Medical Education. 14(6):696-703. https://doi.org/10.4300/JGME-D-22-00088.1

December 19 – December 23, 2022

PUBLICATIONS & PRESENTATIONS
Xie SJ, Kapos FP, Mooney SJ, Mooney S, Stephens KA, Chen C, Hartzler AL, Abhishek Pratap A. Geospatial divide in real-world EHR data: Analytical workflow to assess regional biases and potential impact on health equity. Paper to appear at AMIA Informatics Summit 2023.

Oliver J. Bear Don’t Walk IV, Adrienne Pichon, Harry ReyesNieva, Tony Sun, Jaan Altosaar,Karthik Natarajan, AdlerPerotte,Dina Demner-Fushman, Noémie Elhadad. Auditing Learned Associations in Deep Learning Approaches to Extract Race and Ethnicity from Clinical Text. 2023 AMIA Informatics Summit, Seattle, WA.

ANNOUNCEMENTS
CLIME WILL SPONSOR 10 UW School of Medicine faculty, staff, or students to attend USC Keck School of Medicine Innovations in Medical Education Conference.
The conference is VIRTUAL on Thursday, February 16th and Friday, February 17th, 2023 from 7:30am – 5:30pm Pacific.
More information about the conference here: https://bit.ly/3WjzNwX
Apply for CLIME to sponsor you to attend the conference here: https://bit.ly/3YvyGMK
*The deadline to apply to have CLIME sponsor you is Friday, December 23rd. We will notify all applicants if they have been chosen to be one of the 10 sponsored enrollees. If you are chosen, please do not register for the conference on your own. CLIME will register the selected educators to attend. Email CLIME@UW.EDU with any questions.

Dr. Bryant Karras Appointed to Federal Health Tech Advisory Panel
The Government Accountability Office (GAO) has announced the appointment of seven members, including Bryant Thomas Karras, MD, to the Health Information Technology Advisory Committee (HITAC). The committee provides recommendations to the National Coordinator for health IT on policies, standards, implementation specifications, and certification criteria for implementing a health IT infrastructure that advances the electronic access, exchange, and use of health information.

December 12 – December 16, 2022

PUBLICATIONS & PRESENTATIONS
Yan, C., Yan, Y., Wan, Z., Zhang, Z., Omberg, L., Guinney, J., Mooney, S.D., & Malin, B.A. A Multifaceted benchmarking of synthetic electronic health record generation models. Nat Commun 13, 7609 (2022).  https://www.nature.com/articles/s41467-022-35295-1

UPCOMING FINAL EXAM
Abigail Menschik
Date: Friday, December 16, 2022
Time: 12:30-1:30 pm PST
Zoom link: https://washington.zoom.us/my/peter.th [washington.zoom.us]

Title: Differential expression analysis of TOR3 knockouts in arginine-starved Leishmania major
Abstract: The Arginine Deprivation Response (ADR) pathway is essential for Leishmania parasites to overcome host macrophage defense mechanisms and establish infection. The activation of this pathway appears to rely in part on regulation by target of rapamycin kinase 3 (TOR3), since TOR3 knockouts do not respond to arginine starvation consistent with ADR activation. Here, we investigate the role of TOR3 in response to arginine starvation via TOR3 knockout in Leishmania major. We analyzed mRNA abundance changes in L. major by differential gene expression analysis across four conditions: wild type (WT) in the presence of arginine, WT starved of arginine, knockout (KO) in arginine, and KO starved. As expected, we found a small number of changes between starved and unstarved WT samples, with relatively low magnitude (22 up-regulated, 1 down-regulated; fold change ≤ 2.5). Conversely, comparison of starved and unstarved knockout samples yielded man more differentially expressed genes (1263 up-regulated, 1158 down-regulated) with overall higher fold changes. Comparison of WT and KO samples under starved conditions showed similar results (1533 up-regulated, 1383 down-regulated) while comparison of WT and KO under unstarved showed fewer changes, even in the presence of arginine (463 up-regulated, 261 down-regulated). Together, our results support the hypothesis that TOR3 is involved in the ADR pathway and suggest that it also plays a wider regulatory role in cell homeostasis.

ANNOUNCEMENTS
Congratulations to Post-doc Fellowship Alum Sarah Stansfield!
Sarah Stansfield, PhD (2021) was granted a New Investigator Award from the Center for Aids Research (CFAR) at UW/Fred Hutchinson Cancer Research Center. Sarah’s research is titled Optimizing HIV prevention by personalized assignment to alternate forms of PrEP. To read more about the award, click here.

CLIME Tip Clips Available
CLIME has developed a series of “CLIME Clips!” to offer succinct actionable teaching tips for medical and health professions educators. Check out the rest of our “CLIME Clips!”

December 5 – December 9, 2022

UPCOMING LECTURES AND SEMINARS
BIME 590: See you on January 5^th!

PUBLICATIONS & PRESENTATIONS
Aaltonen HL, O’Reilly MK, Linnau KF, Dong Q, Johnston SK, Jarvik JG, Cross NM. m2ABQ—a proposed refinement of the modified algorithm-based qualitative classification of osteoporotic vertebral fractures. Osteoporosis International. 2022 Nov 7:1-9.

ANNOUNCEMENTS
IAMSE 2023 Winter Webinar Series
Not Just Fun and Games: Game Based Learning in Health Professions Education
*This webinar series is provided by CLIME to all UW affiliated faculty, staff, and students
The Winter 2023 IAMSE Webinar Series will survey the use and benefit of games in health care education and address strategies for incorporating games into the basic science curriculum.  The series will provide an overview of existing literature, including the theories underlying the use of games in medical education, and empirical findings from recent research studies, including a peek into the future of game-based learning. Invited speakers will provide practical strategies to incorporate well-known game formats into instructional sessions such as TV quiz shows, medical escape rooms, virtual reality technologies, and “serious games,” with a special emphasis on immediate feedback and formative assessment.
January 5, 2023: JR Georgiadis – Gamification in Biomedical Education
January 12, 2023: Michelle Carroll Turpin & Jeremey Walker – Trivia Reimagined to Make Questions Fun & Educational
January 19, 2023: Amy Beresheim & Adam Wilson – Escape Rooms to Break Away From the Lull of Lackluster Curricula
January 26, 2023 Michael Cosimini & Sarah Edwards – Card and Board Games for Health Professionals Education
February 2, 2023: Teresa Chan, Eric Gantwerker,,and Satid Thammasitboon – Foresight, Insight and the Quest to Transform Learning through Game- Based Learning
Register to obtain access to the webinars as they are released
Register: https://uw.cloud-cme.com/course/courseoverview?P=29&EID=8509

November 28 – December 2, 2022

UPCOMING LECTURES AND SEMINARS
BIME 590: Thursday, December 8^th – 11-11:50 am
Title: Putting Principles into Practice: Supporting responsible innovation through the AI review process at Google
https://washington.zoom.us/my/peter.th [washington.zoom.us]

Abstract: As an Ethical, Legal, and Social Implications (ELSI) Scholar and AI Ethicist at Google, Dr. Korngiebel will present on how AI reviews are approached in the context of Google’s AI Principles. Starting with a grounding in the main ethical philosophical underpinnings for the AI Principles, the presentation will include how harms and benefits relate to one another, thoughts on process and product examples, and will also touch upon value trade-offs and features that receive special scrutiny.

Presenter bio: Diane M. Korngiebel has been an ELSI (ethical, legal, and social implications) Scholar on the Responsible Innovation Team at Google since May 2022. Dr. Korngiebel started with Google in Oct. 2021 as a Bioethicist on the Google Bioethics team and was a Research Scholar at The Hastings Center, an independent, non-partisan, non-profit bioethics center in Garrison, New York the previous year. Before joining The Hastings Center in 2020, she was an Associate Professor in the Department of Biomedical Informatics and Medical Education and an adjunct Associate Professor in the Department of Bioethics and Humanities at the University of Washington School of Medicine in Seattle; she maintains affiliate faculty status in both UW departments.

Her interests include the ethics of using AI for health and wellness applications, broadly construed, and the potential and limitations of Big Data science, and appropriate (and inappropriate) design and deployment of digital health applications.

Dr. Korngiebel’s work has appeared in the American Journal of Public Health, Nature: Genetics in Medicine, NPJ Digital Medicine, and PLoS Genetics. She was recently the principal investigator on a grant funded by the National Human Genome Research Institute and the National Institutes of Health’s Office of the Director on developing an ethics framework to guide biomedical data scientists constructing data models and algorithms.

UPCOMING FINAL EXAMS – tomorrow (12/2)!
Title: Needs-driven, utility-oriented, standards-based operationalization of artificial intelligence for clinical decision support: a framework with application to suicide prevention
Student: Hannah Burkhardt
Date/Time: Friday, December 2, 2022, 1-3 pm PST
Location: 750 Republican Street, Building E, 1st Floor [google.com], Room E130B
Zoom: https://washington.zoom.us/my/cohenta [washington.zoom.us]

Abstract: While artificial intelligence (AI) technologies increasingly permeate our daily lives, the adoption and impact of AI have fallen short of expectations in healthcare. The challenges of operationalizing AI in healthcare are complex and include interaction design (e.g., poorly designed user interfaces), model formulation (e.g. algorithmic bias, limited practical utility, trustworthiness or interpretability), and workflow context (e.g. a lack of integration into existing workflows; limited model portability). Critically, AI projects must demonstrate overall utility, balancing their costs with the benefits they confer.  To achieve this utility informatics efforts are needed before, during, and after predictive model development, to mediate effective, sustainable, and interoperable AI deployment to support clinical workflows.
In this work, I investigated how human-centered design methods, needs-driven model development, utility-oriented evaluation methods, and standards-based software design can be leveraged collectively to address the unique challenges faced by healthcare AI, and achieve clinically impactful AI implementations. The two key contributions resulting from it are (1) a generalizable framework for the needs-driven operationalization of AI to support healthcare workflows and clinical decision making, and (2) the application of this framework to conceive, implement and evaluate AI support for suicide prevention.
To apply this framework, I used human-centered design methods to assess technological support needs for Caring Contacts, an evidence-based suicide prevention intervention, revealing opportunities for AI-based cognitive support. Using neural transfer learning from publicly available social media data, I developed accurate natural language processing models for risk-based prioritization of patient messages.  Through utility-oriented evaluation metrics, I demonstrated that this model has the potential to positively impact clinical practice. Incorporating this model, I devised a standards-based, reusable, interoperable, workflow-integrated information system for cognitive support of Caring Contacts. I developed blueprints for a FHIR data representation model and information system architecture, and implemented and shared an open-source software application.
Together, this work contributes towards bridging the historical implementation gap by furthering methods for design, development, and delivery of AI-supported interventions, and by guiding future attempts to realize the potential of AI in clinical settings.
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Title: Enhancing Empathy in Text-Based Teletherapy with Emotional State Inference
Student: William Kearns
Date/Time: Friday, December 2, 2022, 9:30-11:30 am PST
Location: Orin Smith Auditorium, South Lake Union, 850 Republican Street, Building C
Zoom: https://washington.zoom.us/my/cohenta [washington.zoom.us]

Abstract: Over half of the U.S. population lives in an area without adequate access to mental health care and the unmet demand for mental health services has shifted to care providers who have not been trained to provide mental health support. This work represents a step toward addressing this supply-demand imbalance by applying recent advances in conversational AI.
The central hypothesis of this work is that both the quality and efficiency of text-based teletherapy can be improved through conversational AI. This was evaluated using mixed-methods approaches with three aims: (1) I explored the ability of computational methods to infer high-fidelity representations of self-reported emotional states, (2) I evaluated these representations as features to predict empathetic responses, (3) I piloted this system as a component of an AI-augmented teletherapy platform for the delivery of problem-solving therapy by nurses and psychologists.
(1) Prior to this work, emotion recognition from conversation (ERC) methods had only been tested on crowdsourced data labels that (a) were inferred by annotators rather than self-described, and (b) did not cover the breadth of emotional states experienced as a result of daily events. This prior work was insufficient to assess the applicability of these methods to characterize self-reported emotional states in the context of check-ins where the emotional states may not be explicitly expressed. To address this gap, I evaluated emotion detection and emotional state inference methods on event-emotional state pairs collected through a daily journaling exercise delivered by SMS. I found that emotional state inference methods improved performance on the task of predicting reported emotions by 71.3% relative to emotion detection methods.
(2) The messages from the daily journaling exercise were labeled by experts based on how they would respond empathetically to them in the context of teletherapy. I found that the addition of emotional state inferences to these messages improved the performance of models on the task of predicting these labels, which in turn indicate appropriate expert-authored empathetic responses to a given utterance.
(3) Quantitative results of the AI-augmented provider platform indicate that the system decreased response times by (+29.34%**; p=0.002), tripled empathetic response accuracy (+200%***; p=0.0001), and increased goal recommendation accuracy (+66.67%**; p=0.001). Structured qualitative interviews indicated that the care providers who used the system felt it would make providing therapy more efficient, lower cognitive load, and be accessible to care providers without mental health training.

UPCOMING GENERAL EXAM
December 5, 2022 – 2-4 pm
Title: Performance and organizational characteristics of analytics teams in healthcare and population health
Student: Ron Buie
Location: Please join us at South Lake Union, 850 Republican St, Building C, Room 123A
Zoom:  https://washington.zoom.us/j/96299494457

Abstract: Business analytics (BA) and business analytics systems (BAS) constitute a family of skills, tools, and processes that help an organization study and communicate information about itself. As defined, BASs have most commonly been used for the collection, management, and presentation of data as it relates to current operations (transactional BAS). However, increasingly, organizations are deploying BASs to identify novel information about the business (change recommending BAS).
As an industry, healthcare has only recently, with the passing of the Affordable Care Act, significantly invested in the infrastructure to collect and utilize data at a scale and fineness necessary for large scale BA. Additionally, the use of these systems has not evolved far beyond their capabilities as a transactional BAS.
There are limited resources available to assist organizations in formally understanding BAS activities and the teams that engage them. Formal descriptions are narrow, often focused on the use of information technology, user acceptance of analytics resources, or high-level descriptions of analytics processes. Furthermore, the healthcare industry presents a new environment with unique cultural, regulatory, and economic hurdles.
In order to improve future evaluation and management of these systems, I intend to identify frameworks and models useful for describing the BAS within the context of organizations (A1) and describe the activities, tools, and context of BASs within health care and population health settings (A2). This research can pave the way for a study of how resultant frameworks are used by different organizations across healthcare and population health, and the use of quantitative approaches to evaluating and monitoring BASs.

ANNOUNCEMENTS
UW is #6 in the World!
The University of Washington rose from No. 7 to No. 6 on the U.S. News & World Report’s Best Global Universities rankings, released this week. The UW maintained its No. 2 ranking among U.S. public institutions. U.S. News also ranked several subjects, and the UW placed in the top 10 in 10 subject areas, including immunology (No. 4), molecular biology and genetics (No. 5) and clinical medicine (No. 6).
See the full report here.

 Dr. Reza Sadeghian (Class of 2019) currently holds a position as Chief Medical Informatics Officer (CMIO) at Hunterdon Medical Center in Flemington, NJ. He received a CPE ( Certified Physician Executive ) credential from American Association for Physician Leadership ( AAPL) this month which is a crucial requirement for the path to receive their fellow status (FAAPL). He also became board eligible with the American College of Healthcare Executives (ACHE) to sit for their board of governor fellow exam. With these credentials, his CI fellowship training at UW, and extensive work experience, he is aiming to get accepted into Yale GELP program next year. Please feel free to connect with him as he always welcomes UW CI fellows and is willing to assist and share his journey to becoming the Chief Medical Information Officer.
His personal page Link
His Linkedin page Link

November 14 – November 18, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590: Thursday, December 1^st – 11-11:50 am
Presenter: Sean Mooney, PhD, FACMI
https://washington.zoom.us/my/peter.th [washington.zoom.us]

PUBLICATIONS & PRESENTATIONS
Annie T. Chen, Uba Backonja, Kenrick D. Cato. Integrating health disparities content into health informatics courses: a cross-sectional survey study and recommendations. Accepted for publication in JAMIA Open.

UPCOMING FINAL EXAMS
Title: Deriving a sociotechnical model for discovery in a genomics-enabled learning health system
Student: Kathleen Muenzen Ferar
Date/Time: Wednesday, November 30th, 2022, 3-5 pm PST
Location: 750 Republican Street, Building E, 1st Floor [google.com], Room E130B
Zoom: https://washington.zoom.us/j/98238845441 [washington.zoom.us]

Abstract: Recent advances in genetic sequencing technologies and analysis tools have made genomic data widely available for medical research. Despite the expectation that genomic data will revolutionize medicine, there exist major evidence gaps in demonstrating the utility of genomic discovery for improving patient outcomes and increasing healthcare efficiency. One promising avenue for reducing this evidence gap and accelerating the pace of clinical genomics discovery is to foster environments in which genomic research and clinical care exist symbiotically. However, the technical and sociocultural requirements for conducting genomic discovery in clinical spaces are not well-defined. The Learning Healthcare System (LHS) framework is one lens through which the barriers and enablers of clinical genomics discovery can be identified and organized. Furthermore, drawing on experiences from clinical genomics research consortia like the Clinical Sequence Evidence-Generating Research (CSER) Consortium and Electronic Medical Records and Genomics (eMERGE) Network can help identify requirements that are unique to genomics discovery initiatives that straddle the research-clinical boundary. In this work, we sought to derive a sociotechnical model for clinical genomics discovery in a genomics enabled LHS (GLHS). We first identified themes and recommendations from the clinical genomics research data integration process in the CSER consortium, and found that the social processes involved in data coordination are tantamount to the informatics tools used to facilitate those processes (Aim 1). We then explored medical geneticist perspectives on clinical genomics discovery by interviewing 20 board-certified medical geneticists in CSER, eMERGE and the University of Washington medical system (Aim 2). Using constructivist grounded theory methods, we developed a preliminary model of GLHS discovery that utilizes the concepts of representation, responsibility, risks & benefits, relationships, and resources (“5R”) to explain negotiations and limits involved in clinical-research integration in genomics. To demonstrate the utility of merging Electronic Health Record (EHR) data with genomic data for discovery, we then conducted a logistic regression-based genome-wide risk assessment for Clostridioides difficile infection (CDI) using merged genetic and EHR data from 12 clinical sites in the eMERGE Network, and found a strong gene-disease association in the HLA-DRB locus (P=8.06 x 10^-14) that predisposes carriers to CDI (Aim 3). Finally, we conducted a systematic literature review of proposed enablers of clinical genomics discovery and synthesized the results from the literature review and Aim 1 with the a priori framework developed in Aim 2 using best-fit framework synthesis (BFFS) (Aim 4). We found that the vast majority of themes identified in the literature were accommodated by the a priori framework, suggesting that the 5R model of GLHS discovery is a reasonable representation of processes involved in learning healthcare. An enhanced 5R sociotechnical model was developed to represent how the negotiation tools identified in the literature could be used to facilitate virtuous cycles of learning in clinical genomics research.

ANNOUNCEMENTS
The paper “‘There’s a problem, now what’s the solution?’: suggestions for technologies to support the menopausal transition from individuals experiencing menopause and healthcare practitioners” by Uba Backonja (Adjunct Faculty), Lisa Taylor-Swanson (NLM Postdoc alum), Andrew Miller (NLM Postdoc alum), Shefali Haldar (PhD alum), and colleagues was a finalist for the Harriet Werley Best Nursing Informatics Paper at the AMIA 2022 Annual Symposium.

Hot Off the Press…
Cohen, TA. Patel, VL. Shortliffe, EH (eds). Intelligent Systems in Medicine and Health: The Role of AI. Springer Verlag 2022.
The book is available through Springer (https://lnkd.in/euiBRbbv [lnkd.in]), and further details are available on our textbook website (https://lnkd.in/eHdEdGVp [lnkd.in]).

 Awards!
As part of Google’s growing efforts to advance health equity and mitigate health disparities, Lisa Dirks (iSchool PhD student) and Wanda Pratt received a $50,000 gift from Google to support Lisa’s thesis work on “Co-designing with Alaska Native communities to communicate equitable health research results.”

Wanda Pratt received a $10,000 gift from Google for her work related to “Gender and Health Informatics.”

November 7 – November 11, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590: Thursday, November 17^th – 11-11:50 am
Title: The ‘Real World’ of Language Technology: A Case Study of Machine Translation”
https://washington.zoom.us/my/peter.th [washington.zoom.us]
 Abstract: Natural language processing (NLP) technologies have transformed how people access information and communicate with one another. Machine translation, one of the most familiar language technologies, has advanced to a high level of quality for dozens of language pairs and is routinely consulted in an array of situations, from medical appointments to social media interactions. However, the overall impact of machine translation has been mixed. There are hundreds of languages for which there are insufficient digital resources to sustain quality machine translation, and errors abound even in translations for so-called “high resource” language pairs, leading to critical misunderstandings. In this talk, I trace some of these issues to the social and political contexts that have shaped the linguistic data landscape and the situations in which machine translation systems are used. I discuss the role of design in addressing some of these issues.
Presenter Bio: Amandalynne Paullada, MA, PhD, is an NLM postdoctoral fellow in the department of Biomedical Informatics and Medical Education at the University of Washington School of Medicine. She completed her PhD in computational linguistics at UW in 2021. Her doctoral work included an examination of the societal impacts of natural language processing technologies, focusing on data collection practices and the design process, and also presented results of a study on the effect of incorporating linguistic structure in computational representations of biomedical relationships. Her ongoing work is concerned with ethical issues in data practices and applications for language technology in healthcare with a focus on justice.

PUBLICATIONS & PRESENTATIONS
NR Johnson, K Dzara, A Pelletier, and IT Goldfarb. 2022. “Medical Students’ Intention to Change After Receiving Formative Feedback: Employing Social Cognitive Theories of Behavior.” Medical Science Educator. https://link.springer.com/article/10.1007/s40670-022-01668-w [link.springer.com]

 

UPCOMING GENERAL EXAM
November 14^th, 2022 – 3 – 5 pm
Title: Explainable query generation for cohort discovery and biomedical reasoning using natural language.
Student: Nic Dobbins
Location: Please join us at South Lake Union, 850 Republican St, Building C, Room 123A or on Zoom.
Abstract: Clinical trials serve a critical role in the generation of medical evidence and progress in biomedical research. In order to identify potential participants, investigators publish eligibility criteria, such as certain conditions, treatments, or laboratory test results. Recruitment of participants remains, however, a major barrier to successful trial completion, and manual chart review of hundreds or thousands of patients to determine a candidate pool can be prohibitively labor- and time-intensive. While cohort discovery tools such as Leaf or i2b2 can serve to assist in finding participants meeting eligibility criteria, such tools nonetheless often have significant learning curves. Moreover, certain complex queries may simply be impossible due to structural limitations on the types of possible queries presented in these tools. An alternative approach is the use of natural language processing (NLP) to automatically analyze eligibility criteria and generate queries. Such approaches have the advantage of leveraging existing eligibility criteria composed in a free-text format researchers are already familiar with. The goal of this project is the development of a cohort discovery tool called LeafAI. In Aim 1, we create a gold-standard annotated corpus of eligibility criteria. In Aim 2, we develop methods for generating data model-agnostic SQL queries and multi-hop biomedical reasoning using a natural language interface with near-human performance. In Aim 3, we develop an interactive chatbot-like web application to enable users to dynamically query clinical databases for cohort discovery using natural language.

ANNOUNCEMENTS
AMIA Best Paper Award
Wanda Pratt and iSchool PhD student Hyeyoung Ryu won an AMIA Best Paper Award at the Annual AMIA Symposium. The award is for work that honors “Samantha Adams’s work at the intersection of informatics and ethics.”
Hyeyoung Ryu and Wanda Pratt. Microaggression clues from social media: revealing and counteracting the suppression of women’s health care, Journal of the American Medical Informatics Association, 29 (2), 257-270.  https://doi.org/10.1093/jamia/ocab208 [doi.org]

AMIA Distinguished Paper Award
Hannah Burkhardt won the Distinguished Paper Award at AMIA this week for the following paper:
Hannah A. Burkhardt, Megan Laine, Amanda Kerbrat, Katherine A. Comtois, Trevor Cohen, Andrea Hartzler. Identifying opportunities for informatics-supported suicide prevention: the case of Caring Contacts. 
Mike Leu Featured
Learn more about Mike Leu and the new Division of Clinical Informatics. He is featured in The Huddle newsletter here. Warning: there is an extremely cute dog picture included!

CLIME Conversation Café
Recognizing Anxiety in Learners
Shannon Uffenbeck, PhD, Assistant Professor, Alaska Academic Support Coordinator
December 1, 2022, 12:00 pm – 1:00 pm (PT)
Zoom (Online) – Register: https://bit.ly/3Vfc8hr [bit.ly]

October 31 – November 4, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590: Thursday, November 10^th – 11-11:50 am
Title: Patient profiles to target engagement and health care delivery strategies
https://washington.zoom.us/my/peter.th [washington.zoom.us]
Presenter: Casey Overby Taylor, Ph.D.
Associate Professor of Medicine and Biomedical Engineering
Division of General Internal Medicine, Biomedical Informatics & Data Science Section
Interim Associate Director, Institute for Computational Medicine
Johns Hopkins University School of Medicine

Alumni Panel November 9th
Please join us for an “Alumni panel” of local BIME PhD Alumni on Wed, Nov 9th at 10:30am (Room 235, in the new Health Sciences Education Bldg). Each alumni will comment on the aspects of the BIME program that helped (or didn’t help!) on their career path to date.
Panel Members:

• • Tim Bergquist (2021), Research Scientist at Sage Bionetworks
  • Ryan James (2019), CEO Dopl Technologies
  • Ross Lordon (2019), UX Researcher at Microsoft
  • Lauren Snyder (2021), Senior Program Officer at The Gates Foundation
  • Lucy Lu Wang (2019), Assistant Professor at the UW iSchool

(BIME graduation dates indicated in parentheses)
The goal is to showcase the variety of careers one can pursue with a PhD in BHI, and allow current students the chance to ask questions of our recent graduates.

PUBLICATIONS & PRESENTATIONS
Jablonowski K, Hooker B. Delayed Vigilance: A Comment on Myocarditis in Association with the COVID-19 Injections. International Journal of Vaccine Theory, Practice, and Research 2(2), October17, 2022 p651.1. https://ijvtpr.com/index.php/IJVTPR/article/view/61/108 [ijvtpr.com]

ANNOUNCEMENTS
UW is #6 in the World!
The University of Washington rose from No. 7 to No. 6 on the U.S. News & World Report’s Best Global Universities rankings, released this week. The UW maintained its No. 2 ranking among U.S. public institutions. U.S. News also ranked several subjects, and the UW placed in the top 10 in 10 subject areas, including immunology (No. 4), molecular biology and genetics (No. 5) and clinical medicine (No. 6).

October 24 – 28, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590: Thursday, November 3^rd – 11-11:50 am
Title: Reading and writing academic papers:  citations are mini-summaries with a view
https://washington.zoom.us/my/peter.th [washington.zoom.us]

Presenter Bio: Lucy Vanderwende, Ph.D., is Affiliate Associate Faculty at University of Washington Department of Biomedical Health Informatics, a member of the UW BioNLP group, who are using NLP technology to extract critical information from patient reports. She holds a Ph.D. in Computational Linguistics from Georgetown University. Lucy worked at Microsoft Research, Redmond, WA, from 1992 – 2018. She first was a member of the 7 person team who created the Microsoft Grammar Checker, a product that has impacted people all over the world. Her work in Natural Language Processing since 1998 includes research in Common Sense Reasoning and Knowledge Acquisition, in addition to Information Retrieval, Summarization, Opinion Mining, Question Generation, and Knowledge Base Population. As a member of BIME, Lucy collaborates with Meliha Yetisgen on the definition of schemas for extracting information from Electronic Health Records. Interests include automated acquisition of semantic knowledge; information extraction from clinical records; robust, broad-coverage language analysis.

Abstract: This talk will take time to reflect on how we read and write research papers. The pace of research and electronic publishing gives us access to large numbers of papers in any field, yet makes it more challenging to assess the quality of a specific paper and more challenging to find the correct works to support or refute findings. This talk will show how we can use the sentences that describe a referenced paper as a retrospective abstract, one that authors may not have anticipated at the moment of writing. I will talk about a dataset we defined as a task for summarization at the Text Analysis Conference, sponsored by NIST, enabling computational systems to identify these citing sentences and abstracts automatically. This talk will highlight the importance of writing good citing sentences as an author and the importance of close-reading citing sentences to discern any opinions the author may have about the referenced paper.

UPCOMING GENERAL EXAM

November 14th, 2022 – 3-5 pm

Title: Explainable query generation for cohort discovery and biomedical reasoning using natural language.
Student: Nic Dobbins

Abstract: Clinical trials serve a critical role in the generation of medical evidence and progress in biomedical research. In order to identify potential participants, investigators publish eligibility criteria, such as certain conditions, treatments, or laboratory test results. Recruitment of participants remains, however, a major barrier to successful trial completion, and manual chart review of hundreds or thousands of patients to determine a candidate pool can be prohibitively labor- and time-intensive. While cohort discovery tools such as Leaf or i2b2 can serve to assist in finding participants meeting eligibility criteria, such tools nonetheless often have significant learning curves. Moreover, certain complex queries may simply be impossible due to structural limitations on the types of possible queries presented in these tools. An alternative approach is the use of natural language processing (NLP) to automatically analyze eligibility criteria and generate queries. Such approaches have the advantage of leveraging existing eligibility criteria composed in a free-text format researchers are already familiar with. The goal of this project is the development of a cohort discovery tool called LeafAI. In Aim 1, we create a gold-standard annotated corpus of eligibility criteria. In Aim 2, we develop methods for generating data model-agnostic SQL queries and multi-hop biomedical reasoning using a natural language interface with near-human performance. In Aim 3, we develop an interactive chatbot-like web application to enable users to dynamically query clinical databases for cohort discovery using natural language.

Location: Please join us at South Lake Union, 850 Republican St, Building C, Room 123A or on Zoom.

ANNOUNCEMENTS

Applications Are Now Being Accepted for the TL1 Translational Research Program 2023 Cohort!

The Institute of Translational Health Sciences TL1 program [iths.org], is a one-year NIH funded program that offers rigorous training in clinical and translational research for pre-doctoral students in an interdisciplinary cohort environment. This program provides funding, mentorship, and training. While in the program, participants will receive a stipend, research funds and tuition support.

We would like to encourage applicants interested in all types of research, including patient-oriented research, translational research, small- and large-scale clinical investigation and trials, epidemiologic and natural history studies, clinical and biomedical informatics, health services research, and health behavior research to apply. The application deadline is December 16, 2022. Learn more and apply on the ITHS website [iths.org].

We’ll be having a few information sessions for anyone interested in attending and learning more about the program.

• • • Wednesday, October 26^th, 2022 from 4-4:30PM (PST); Register Here [washington.zoom.us]
    • Thursday, November 3^rd, 2022 from 12-12:30PM (PST);Register Here [washington.zoom.us]

For questions, please contact Milu Worku at mworku@uw.edu.

October 17 – 21, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590: Thursday, October 27 – 11-11:50 am
Title: Inferring Race and Ethnicity from Clinical Notes: Annotation, Model Auditing, and Ethical Implications
https://washington.zoom.us/my/peter.th [washington.zoom.us]

Presenter Bio: Oliver J. Bear Don’t Walk IV is a citizen of the Apsáalooke Nation in present day Montana and is a Postdoctoral Scholar and AIM-AHEAD Research Fellow at the University of Washington in Biomedical Informatics and Medical Education. They completed their PhD in biomedical informatics at Columbia University and received their bachelors in Math and Computational Science from Stanford University. Oliver’s research is at the intersection of clinical natural language processing (NLP), fairness, and ethics. His thesis focused on the technical and ethical aspects of extracting race and ethnicity from clinical notes and identifying biased associations in NLP models trained to extract this information. Oliver is thankful for the community support which has brought him this far, and as such Oliver pays it forward through teaching and mentorship positions such as serving as an organizer and faculty for IndigiData and a co-chair for the American Medical Informatics Association’s Diversity, Equity, and Inclusion Committee.

Abstract: Many areas of clinical informatics research rely on accurate and complete race and ethnicity (RE) patient information. Structured data in the electronic health record (EHR) is an easily accessible source for patient-level information, however RE information is often missing or inaccurate in structured EHR data. Clinical notes provide a rich source of information that can be leveraged to increase granularity and/or recover RE information missing in structured data through state-of-the-art clinical natural language processing (NLP) approaches. However, NLP has also been shown to inherit, exacerbate, and create new biased and harmful associations, especially in modern deep learning approaches. In this talk, I will present results from my dissertation exploring the relationships between explicit mentions of RE and RE inferences in clinical text made by clinicians. I will also present results from? an audit for bias in deep NLP models trained to identify RE in clinical text. This work is underpinned by a (soon to be) publicly available gold-standard corpus with annotations for information related to RE and RE labels. These gold-standard annotations allowed us to explore what kinds of information are used to describe RE categories and what kinds of associations deep NLP models learn when identifying RE in clinical text.

PUBLICATIONS & PRESENTATIONS

Nguemeni Tiako MJ, Rahman F, Sabin J, Black A, Boatright D and Genao I (2022). Piloting web-based structural competency modules among internal medicine residents and graduate students in public health. Front. Public Health10:901523. October 14, 2022.

ANNOUNCEMENTS

Janice Sabin is Co-Investigator on a new NIH grant: “PAINED: Project Addressing INequities in the Emergency Department.”  Principal Investigator: Monika Goyal, MD, MSCE, Children’s National Hospital Research Institute, Washington, DC.

October 10 – 14, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590: Thursday, October 20 – 11-11:50 am
Title: The CORES Story: Creating Something New & Needed
https://washington.zoom.us/my/peter.th [washington.zoom.us]

Abstract: Health systems in the United States spent $14.5 billion on Electronic Health Records systems in 2019, and are expected to spend $19.9 billion in 2024. Many clinical users of these systems do not feel that they are getting good usability value for that much spending. What kinds of things could be wrong with software systems that have so much money invested in them yet the users would feel they offer poor usability? In this talk, you’ll learn about the difference between design and user experience. You’ll see an example of an EHR quality improvement project that became academic research. You’ll be able to explain the real goals of record-keeping in medicine, from a clinician’s point of view. You’ll be able to describe one model of taking academic innovation to commercial product.

Speaker Bio: Erik G. Van Eaton, MD, FACS, is an Associate Professor of Surgery and Surgical Critical Care, and an Adjunct Associate Professor of Biomedical Informatics and Medical Education at the University of Washington and Harborview Medical Centers, in Seattle, Washington. Dr. Van Eaton specializes in Trauma Surgery, Surgical Critical Care, Emergency General Surgery, Acute Care Surgery, and General Surgery. As part of his General Surgery practice, Dr. Van Eaton’s clinical focus is complex hernia operations, surgical treatment of fistula, intestinal surgery, gallbladder surgery, and reconstructive abdominal procedures after recovery from major trauma A trained medical informatics scientist, Dr. Van Eaton studies how Electronic Health Record (EHR)-embedded software can support core clinical workflows. Research avenues include observational studies of EHR use in physician handoffs, subjective evaluations of EHR-related burnout and stress, and impact of EHR-embedded software and mobile apps on quality metrics. Dr. Van Eaton builds collaborative relationships among successful clinical informatics projects health systems throughout the world to bring high-performance clinical information management to bedside decisions. As an NIH NLM Fellow at UW, Dr. Van Eaton developed a computerized rounding and sign-out software system that changed the ways in which residents communicate about, and manage “ownership” of, their patients. This work led to a spin-out healthcare information technology company from the University of Washington in 2011 called TransformativeMed Inc.

PUBLICATIONS & PRESENTATIONS

Jim Phuong was invited to participate in the plenary session of the International Academy of Health Sciences Informatics (IAHSI), the Honorific International Society of AMIA, at the 2022 AMIA Annual Meeting. This year’s plenary session focuses on the topic of informatics and climate change. Jim will present an overview of his latest JAMIA publication.

Phuong J, Riches NO, Calzoni L, Datta G, Duran D, Lin AY, Singh RP, Solomonides AE, Whysel NY, Kavuluru R. Toward informatics-enabled preparedness for natural hazards to minimize health impacts of climate change. J Am Med Inform Assoc. 2022 Sep 12:ocac162. doi: 10.1093/jamia/ocac162 [10.1093]. Epub ahead of print. PMID: 36094062.

October 3 – 7, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590
10/13/2022
Integrating longitudinal clinical phenotype and exposome into multiomics at scale
Jennifer Hadlock, MD
Assistant Professor, Director of Medical Data Science
Institute for Systems Biology

Bio: Dr. Jennifer Hadlock is an Assistant Professor and Director of Medical Data Science at the Institute for Systems Biology (ISB). Her interdisciplinary lab investigates ways to accelerate research into transitions between wellness and disease by combining machine learning, biomedical logic and knowledge graphs. Specific areas of focus include explainable decision support for immune-mediated inflammatory diseases, chronic multimorbidity and maternal/fetal health. As a Principal Investigator in the NIH NCATS Biomedical Translator Consortium, Dr. Hadlock works closely with national experts to develop data harmonization and analytic methods for sharing knowledge from real-world data at scale, while preserving patient privacy. She has also led advances in scalable machine learning for research with ISB’s affiliate partner, Providence St Joseph Health, a healthcare system that provides care through 51 hospitals and 1085 clinics across seven states, with records for over 20,000,000 patients. In addition, she supports integration of longitudinal real world data into multiomic studies. Her lab is funded by grants from NIH institutes, nonprofit organizations and industry. Prior to joining ISB, she led engineering teams at Microsoft for 15 years, including work on natural language processing (NLP), geographic information systems (GIS) and digital imaging technology, used by hundreds of millions of people worldwide. She subsequently earned an MD from the University of Washington, with a focus on care for underserved populations.

PUBLICATIONS & PRESENTATIONS
Hartzler AL, Bartlett LE, Hobler MR, Reid N, Pryor JB, Kapnadak SG, Berry DL, Lober WB, Goss CH, Ramos KJ. Take On Transplant: Human-centered design of a patient education tool to facilitate informed discussions about lung transplant among people with cystic fibrosis. J Am Med Inform Assoc. 2022 Sep 29;ocac176. doi: 10.1093/jamia/ocac176. Online ahead of print. PMID: 36173364.

Segal CD, Lober WB, Revere D, Lorigan D, Karras BT, Baseman JG. Trading-off privacy and utility: the Washington State experience assessing the performance of a public health digital exposure notification system for coronavirus disease 2019, Journal of the American Medical Informatics Association, 2022;, ocac178, https://doi.org/10.1093/jamia/ocac178

ANNOUNCEMENTS
Andrea Hartzler and Lauren Snyder were invited to present their recent JAMIA paper at the JAMIA Journal Club Webinar on Thursday Oct 13 12-1pm PST. https://amia.org/education-events/education-catalog/jamia-journal-club-webinar-october-2022 [amia.org]

September 26 – 30, 2022

UPCOMING LECTURES AND SEMINARS

BIME 590

Thursday, October 6^th

PLEASE NOTE: Class is in SLU, Building C, in the Orin Smith Auditorium (NOT in the normal room!)

Title: Comprehension, utility, and preferences of prostate cancer survivors for visual timelines of patient-reported outcomes co-designed for limited graph literacy: meters and emojis over comics

Bio: Andrea Hartzler is an Associate Professor in the Department of Biomedical Informatics and Medical Education at the University of Washington and Co-directs the Clinical Informatics and Patient-Centered Technologies Graduate program. She also serves as a clinical informatics leader in operational efforts at University of Washington Medicine. Dr. Hartzler’s research spans consumer health informatics, clinical informatics, and human-computer interaction with a focus on the human-centered design of technologies that promote health equity. Dr. Hartzler earned her PhD in Biomedical Informatics at the University of Washington in 2009. She was an Investigator at Kaiser Permanente Washington Health Research Institute before joining the faculty at University of Washington School of Medicine in 2017.

Abstract: Visual timelines of patient-reported outcomes (PRO) that help survivors track longitudinal trends in symptoms may be most effective when designed with deliberate consideration of users. Yet, graph literacy is often overlooked as a design constraint, particularly when users with limited graph literacy are not engaged in their development. Building upon our prior work co-designing longitudinal PRO visualizations for survivors with limited literacy, we engaged 18 prostate cancer survivors in a user study to assess comprehension, utility, and preferences among 4 prototypes: Meter, Words, Comic, and Emoji. This talk with cover study findings, design considerations for users with limited graph literacy, and lessons on engaging hard to reach groups in remote user testing.

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CLIME Grand Rounds
Allowing Medicine to Flourish Again: Cultivating Professional Identity in Medical Education
Audrea Burns, PhD, Associate Professor of Pediatrics, Baylor College of Medicine
October 13, 2022
12:00pm – 1:00pm (PT)
Zoom (Online)

Register here:  https://uw.cloud-cme.com/course/courseoverview?P=29&EID=8414 [uw.cloud-cme.com]

ANNOUNCEMENTS

Yong Choi, PhD, will be joining the University of Pittsburgh School of Health and Rehabilitation Sciences Department of Health Information Management as an Assistant Professor starting in October. Congratulations Yong!